A spatiotemporal blueprint of the planarian redox status: from drivers to physiological responses.

  • Karen Smeets (Supervisor)
  • Van Belleghem, F. (Assessment committee member)
  • Tom Artois (Assessment committee member)
  • Liesbet Temmerman (Assessment committee member)
  • Francesc Cebrià (Assessment committee member)
  • Jordi Solana (Assessment committee member)
  • Jan Colpaert (Assessment committee chair)

Activity: PhD supervision and PhD examination types › PhD examination › Academic

Description

The data presented in this PhD show the importance of the dynamic redox system in different physiological events in the planarian Schmidtea mediterranea, and the role of the ROS-mediated MAPK/ERK pathway in regeneration initiation and patterning. The thesis shows the value of monitoring dynamic processes such as ROS activity or the use of endogenous fluorophores, via real-time in vivo imaging. The spatiotemporal
blueprint of the planarian redox system is far from fully mapped. However, this thesis is a beginning, as even the longest way starts with the first step.
Period26 Jan 2022
ExamineeVincent Jaenen
Examination held at
  • Hasselt University
Degree of RecognitionInternational