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An ECHO of Cartilage: In Silico Prediction of Combinatorial Treatments to Switch Between Transient and Permanent Cartilage Phenotypes With Ex Vivo Validation

  • Sakshi Khurana
  • , Stefano Schivo
  • , Jacqueline R. M. Plass
  • , Nikolas Mersinis
  • , Jetse Scholma
  • , Johan Kerkhofs
  • , Leilei Zhong
  • , Jaco van de Pol
  • , Rom Langerak
  • , Liesbet Geris
  • , Marcel Karperien
  • , Janine N. Post

    Research output: Contribution to journalArticleAcademicpeer-review

    1   Link opens in a new tab Citation (Web of Science)
    Original languageEnglish
    Article number732917
    Number of pages21
    JournalFrontiers in bioengineering and biotechnology
    Volume9
    DOIs
    Publication statusPublished - 15 Nov 2021

    Keywords

    • ARTICULAR-CARTILAGE
    • BIOLOGICAL PATHWAY DYNAMICS
    • BMP7
    • BONE
    • CHONDROCYTE DIFFERENTIATION
    • CHONDROGENESIS
    • GROWTH-PLATE
    • HORMONE-RELATED PEPTIDE
    • IGF
    • JOINT FORMATION
    • PROTEIN-PHOSPHORYLATION
    • PTHrP
    • SOX9
    • chondrogenesis
    • computational model
    • hypertrophy
    • signal transduction

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