In dynamic value networks (VNs), knowledge serves as a basis for close collaboration of actors (i.e. firms with their partners and customers) to enhance co-creation of integrated solutions. In order to provide a technical foundation for seamless knowledge transfer among actors, VNs require distributed and interoperable intra- and inter-organizational knowledge management systems (KMS), which rely largely on advanced information and communication technology (ICT). KMS cannot be seen as stand-alone information systems but should address a variety of issues (e.g. organizational or social issues) in relation to knowledge management. Therefore, the new generation of such complex systems, appropriate for VNs, must deal with this variety of issues, ranging from merely business-oriented to pure technologically-oriented issues. Although scholars have studied knowledge transfer and ICT issues in VN settings, their insights and results remain fragmented because of the diverse research efforts from different perspectives (either from a more business or a more technical perspective). This necessitates that a broader perspective needs to be established. This study endeavors to address simultaneously potential issues of both knowledge transfer and ICT in a VN by developing a comprehensive integrated framework. The development of the framework is based on a three-step methodology which comprises the exploration and classification of generic ICT issues in a VN setting, and subsequently integrating knowledge transfer issues with ICT issues. The proposed integrated framework provides a well-structured theoretical basis for future KMS requirement engineering in VN environments.