Compound Lipophilicity as a Descriptor to Predict Binding Affinity (1/K-m) in Mammals

Alessandra Pirovano*, Mark A. J. Huijbregts, Ad M. J. Ragas, A. Jan Hendriks

*Corresponding author for this work

    Research output: Contribution to journalArticleAcademicpeer-review

    5 Citations (Web of Science)
    Original languageEnglish
    Pages (from-to)5168-5174
    Number of pages7
    JournalEnvironmental Science & Technology
    Volume46
    Issue number9
    DOIs
    Publication statusPublished - 1 May 2012

    Keywords

    • FLAVIN-CONTAINING MONOOXYGENASES
    • DRUG-METABOLISM
    • HUMAN P450S
    • CYTOCHROME-P450
    • SPECIFICITY
    • ASSESSMENTS
    • ALDEHYDES
    • TOXICITY
    • KINETICS
    • ENZYMES

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