ECHO, the executable CHOndrocyte: A computational model to study articular chondrocytes in health and disease

Stefano Schivo; Sakshi Khurana; Kannan Govindaraj; Jetse Scholma; Johan Kerkhofs; Leilei Zhong; Xiaobin Huang; Jaco van de Pol; Rom Langerak; André J van Wijnen; Liesbet Geris; Marcel Karperien; Janine N Post

doi:10.1016/j.cellsig.2019.109471

ECHO, the executable CHOndrocyte: A computational model to study articular chondrocytes in health and disease

Stefano Schivo, Sakshi Khurana, Kannan Govindaraj, Jetse Scholma, Johan Kerkhofs, Leilei Zhong, Xiaobin Huang, Jaco van de Pol, Rom Langerak, André J van Wijnen, Liesbet Geris, Marcel Karperien, Janine N Post^*

^*Corresponding author for this work

Department of Computer Science

Research output: Contribution to journal › Article › Academic › peer-review

6 Citations (Web of Science)

Original language	English
Article number	109471
Number of pages	17
Journal	Cellular Signalling
Volume	68
Early online date	11 Dec 2019
DOIs	https://doi.org/10.1016/j.cellsig.2019.109471
Publication status	Published - Apr 2020

Keywords

ADIPOSE-TISSUE
ANIMO
BETA TGF-BETA
CARTILAGE
Cartilage
Chondrocyte
Computational model
ECHO
ENDOCHONDRAL OSSIFICATION
GROWTH-FACTOR-I
Hypertrophy
INDIAN HEDGEHOG
Interleukin-1beta
JOINT FORMATION
MESENCHYMAL STEM-CELLS
OSTEOGENIC DIFFERENTIATION
Osteoarthritis
RUNX2
SOX9
TERMINAL DIFFERENTIATION

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Schivo, S., Khurana, S., Govindaraj, K., Scholma, J., Kerkhofs, J., Zhong, L., Huang, X., van de Pol, J., Langerak, R., van Wijnen, A. J., Geris, L., Karperien, M., & Post, J. N. (2020). ECHO, the executable CHOndrocyte: A computational model to study articular chondrocytes in health and disease. Cellular Signalling, 68, Article 109471. https://doi.org/10.1016/j.cellsig.2019.109471

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title = "ECHO, the executable CHOndrocyte: A computational model to study articular chondrocytes in health and disease",

keywords = "ADIPOSE-TISSUE, ANIMO, BETA TGF-BETA, CARTILAGE, Cartilage, Chondrocyte, Computational model, ECHO, ENDOCHONDRAL OSSIFICATION, GROWTH-FACTOR-I, Hypertrophy, INDIAN HEDGEHOG, Interleukin-1beta, JOINT FORMATION, MESENCHYMAL STEM-CELLS, OSTEOGENIC DIFFERENTIATION, Osteoarthritis, RUNX2, SOX9, TERMINAL DIFFERENTIATION",

author = "Stefano Schivo and Sakshi Khurana and Kannan Govindaraj and Jetse Scholma and Johan Kerkhofs and Leilei Zhong and Xiaobin Huang and {van de Pol}, Jaco and Rom Langerak and {van Wijnen}, {Andr{\'e} J} and Liesbet Geris and Marcel Karperien and Post, {Janine N}",

year = "2020",

month = apr,

doi = "10.1016/j.cellsig.2019.109471",

language = "English",

volume = "68",

journal = "Cellular Signalling",

issn = "0898-6568",

publisher = "Elsevier Inc.",

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TY - JOUR

T1 - ECHO, the executable CHOndrocyte

T2 - A computational model to study articular chondrocytes in health and disease

AU - Schivo, Stefano

AU - Khurana, Sakshi

AU - Govindaraj, Kannan

AU - Scholma, Jetse

AU - Kerkhofs, Johan

AU - Zhong, Leilei

AU - Huang, Xiaobin

AU - van de Pol, Jaco

AU - Langerak, Rom

AU - van Wijnen, André J

AU - Geris, Liesbet

AU - Karperien, Marcel

AU - Post, Janine N

PY - 2020/4

Y1 - 2020/4

KW - ADIPOSE-TISSUE

KW - ANIMO

KW - BETA TGF-BETA

KW - CARTILAGE

KW - Cartilage

KW - Chondrocyte

KW - Computational model

KW - ECHO

KW - ENDOCHONDRAL OSSIFICATION

KW - GROWTH-FACTOR-I

KW - Hypertrophy

KW - INDIAN HEDGEHOG

KW - Interleukin-1beta

KW - JOINT FORMATION

KW - MESENCHYMAL STEM-CELLS

KW - OSTEOGENIC DIFFERENTIATION

KW - Osteoarthritis

KW - RUNX2

KW - SOX9

KW - TERMINAL DIFFERENTIATION

U2 - 10.1016/j.cellsig.2019.109471

DO - 10.1016/j.cellsig.2019.109471

M3 - Article

C2 - 31837466

SN - 0898-6568

VL - 68

JO - Cellular Signalling

JF - Cellular Signalling

M1 - 109471

ER -

ECHO, the executable CHOndrocyte: A computational model to study articular chondrocytes in health and disease

Keywords

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