ECHO, the executable CHOndrocyte: A computational model to study articular chondrocytes in health and disease

Stefano Schivo; Sakshi Khurana; Kannan Govindaraj; Jetse Scholma; Johan Kerkhofs; Leilei Zhong; Xiaobin Huang; Jaco van de Pol; Rom Langerak; André J van Wijnen; Liesbet Geris; Marcel Karperien; Janine N Post

doi:10.1016/j.cellsig.2019.109471

ECHO, the executable CHOndrocyte: A computational model to study articular chondrocytes in health and disease

Stefano Schivo
, Sakshi Khurana
, Kannan Govindaraj
, Jetse Scholma
, Johan Kerkhofs
, Leilei Zhong
, Xiaobin Huang
, Jaco van de Pol
, Rom Langerak
, André J van Wijnen
, Liesbet Geris
, Marcel Karperien
, Janine N Post^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

6 Citations (Web of Science)

Original language	English
Article number	109471
Number of pages	17
Journal	Cellular Signalling
Volume	68
Early online date	11 Dec 2019
DOIs	https://doi.org/10.1016/j.cellsig.2019.109471
Publication status	Published - Apr 2020

Keywords

ADIPOSE-TISSUE
ANIMO
BETA TGF-BETA
CARTILAGE
Cartilage
Chondrocyte
Computational model
ECHO
ENDOCHONDRAL OSSIFICATION
GROWTH-FACTOR-I
Hypertrophy
INDIAN HEDGEHOG
Interleukin-1beta
JOINT FORMATION
MESENCHYMAL STEM-CELLS
OSTEOGENIC DIFFERENTIATION
Osteoarthritis
RUNX2
SOX9
TERMINAL DIFFERENTIATION

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Schivo, S., Khurana, S., Govindaraj, K., Scholma, J., Kerkhofs, J., Zhong, L., Huang, X., van de Pol, J., Langerak, R., van Wijnen, A. J., Geris, L., Karperien, M., & Post, J. N. (2020). ECHO, the executable CHOndrocyte: A computational model to study articular chondrocytes in health and disease. Cellular Signalling, 68, Article 109471. https://doi.org/10.1016/j.cellsig.2019.109471

@article{c8afbf16bbcd4716a850c0f96f5f0326,

title = "ECHO, the executable CHOndrocyte: A computational model to study articular chondrocytes in health and disease",

keywords = "ADIPOSE-TISSUE, ANIMO, BETA TGF-BETA, CARTILAGE, Cartilage, Chondrocyte, Computational model, ECHO, ENDOCHONDRAL OSSIFICATION, GROWTH-FACTOR-I, Hypertrophy, INDIAN HEDGEHOG, Interleukin-1beta, JOINT FORMATION, MESENCHYMAL STEM-CELLS, OSTEOGENIC DIFFERENTIATION, Osteoarthritis, RUNX2, SOX9, TERMINAL DIFFERENTIATION",

author = "Stefano Schivo and Sakshi Khurana and Kannan Govindaraj and Jetse Scholma and Johan Kerkhofs and Leilei Zhong and Xiaobin Huang and \{van de Pol\}, Jaco and Rom Langerak and \{van Wijnen\}, \{Andr{\'e} J\} and Liesbet Geris and Marcel Karperien and Post, \{Janine N\}",

year = "2020",

month = apr,

doi = "10.1016/j.cellsig.2019.109471",

language = "English",

volume = "68",

journal = "Cellular Signalling",

issn = "0898-6568",

publisher = "Elsevier Inc.",

}

TY - JOUR

T1 - ECHO, the executable CHOndrocyte

T2 - A computational model to study articular chondrocytes in health and disease

AU - Schivo, Stefano

AU - Khurana, Sakshi

AU - Govindaraj, Kannan

AU - Scholma, Jetse

AU - Kerkhofs, Johan

AU - Zhong, Leilei

AU - Huang, Xiaobin

AU - van de Pol, Jaco

AU - Langerak, Rom

AU - van Wijnen, André J

AU - Geris, Liesbet

AU - Karperien, Marcel

AU - Post, Janine N

PY - 2020/4

Y1 - 2020/4

KW - ADIPOSE-TISSUE

KW - ANIMO

KW - BETA TGF-BETA

KW - CARTILAGE

KW - Cartilage

KW - Chondrocyte

KW - Computational model

KW - ECHO

KW - ENDOCHONDRAL OSSIFICATION

KW - GROWTH-FACTOR-I

KW - Hypertrophy

KW - INDIAN HEDGEHOG

KW - Interleukin-1beta

KW - JOINT FORMATION

KW - MESENCHYMAL STEM-CELLS

KW - OSTEOGENIC DIFFERENTIATION

KW - Osteoarthritis

KW - RUNX2

KW - SOX9

KW - TERMINAL DIFFERENTIATION

U2 - 10.1016/j.cellsig.2019.109471

DO - 10.1016/j.cellsig.2019.109471

M3 - Article

C2 - 31837466

SN - 0898-6568

VL - 68

JO - Cellular Signalling

JF - Cellular Signalling

M1 - 109471

ER -

ECHO, the executable CHOndrocyte: A computational model to study articular chondrocytes in health and disease

Keywords

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