Predicting the oral uptake efficiency of chemicals in mammals: Combining the hydrophilic and lipophilic range

Isabel A. O'Connor; Mark A. J. Huijbregts; Ad M. J. Ragas; A. Jan Hendriks

doi:10.1016/j.taap.2012.10.015

Predicting the oral uptake efficiency of chemicals in mammals: Combining the hydrophilic and lipophilic range

Isabel A. O'Connor^*
, Mark A. J. Huijbregts
, Ad M. J. Ragas
, A. Jan Hendriks

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

10 Citations (Web of Science)

Original language	English
Pages (from-to)	150-156
Number of pages	7
Journal	Toxicology and Applied Pharmacology
Volume	266
Issue number	1
DOIs	https://doi.org/10.1016/j.taap.2012.10.015
Publication status	Published - 1 Jan 2013

Keywords

Bioaccumulation
Oral uptake efficiency
Hydrogen bond donor
Mammals
Mechanistic model
Hydrophilic
INTESTINAL-ABSORPTION
HYDROPHOBIC CHEMICALS
DRUG ABSORPTION
PARTITION-COEFFICIENTS
MEMBRANE PERMEATION
RATE CONSTANTS
TRANSPORT
BIOCONCENTRATION
PERMEABILITY
FISH

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10.1016/j.taap.2012.10.015

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title = "Predicting the oral uptake efficiency of chemicals in mammals: Combining the hydrophilic and lipophilic range",

keywords = "Bioaccumulation, Oral uptake efficiency, Hydrogen bond donor, Mammals, Mechanistic model, Hydrophilic, INTESTINAL-ABSORPTION, HYDROPHOBIC CHEMICALS, DRUG ABSORPTION, PARTITION-COEFFICIENTS, MEMBRANE PERMEATION, RATE CONSTANTS, TRANSPORT, BIOCONCENTRATION, PERMEABILITY, FISH",

author = "O'Connor, \{Isabel A.\} and Huijbregts, \{Mark A. J.\} and Ragas, \{Ad M. J.\} and Hendriks, \{A. Jan\}",

year = "2013",

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doi = "10.1016/j.taap.2012.10.015",

language = "English",

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T1 - Predicting the oral uptake efficiency of chemicals in mammals

T2 - Combining the hydrophilic and lipophilic range

AU - O'Connor, Isabel A.

AU - Huijbregts, Mark A. J.

AU - Ragas, Ad M. J.

AU - Hendriks, A. Jan

PY - 2013/1/1

Y1 - 2013/1/1

KW - Bioaccumulation

KW - Oral uptake efficiency

KW - Hydrogen bond donor

KW - Mammals

KW - Mechanistic model

KW - Hydrophilic

KW - INTESTINAL-ABSORPTION

KW - HYDROPHOBIC CHEMICALS

KW - DRUG ABSORPTION

KW - PARTITION-COEFFICIENTS

KW - MEMBRANE PERMEATION

KW - RATE CONSTANTS

KW - TRANSPORT

KW - BIOCONCENTRATION

KW - PERMEABILITY

KW - FISH

U2 - 10.1016/j.taap.2012.10.015

DO - 10.1016/j.taap.2012.10.015

M3 - Article

SN - 0041-008X

VL - 266

SP - 150

EP - 156

JO - Toxicology and Applied Pharmacology

JF - Toxicology and Applied Pharmacology

IS - 1

ER -

Predicting the oral uptake efficiency of chemicals in mammals: Combining the hydrophilic and lipophilic range

Keywords

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