White noise speech illusion and psychosis expression: An experimental investigation of psychosis liability

Lotta-Katrin Pries, Sinan Guloksuz, Claudia Menne-Lothmann, Jeroen Decoster, Ruud van Winkel, Dina Collip, Philippe Delespaul, Marc De Hert, Catherine Derom, Evert Thiery, Nele Jacobs, Marieke Wichers, Claudia J P Simons, Bart P F Rutten, Jim van Os

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

BACKGROUND: An association between white noise speech illusion and psychotic symptoms has been reported in patients and their relatives. This supports the theory that bottom-up and top-down perceptual processes are involved in the mechanisms underlying perceptual abnormalities. However, findings in nonclinical populations have been conflicting.

OBJECTIVES: The aim of this study was to examine the association between white noise speech illusion and subclinical expression of psychotic symptoms in a nonclinical sample. Findings were compared to previous results to investigate potential methodology dependent differences.

METHODS: In a general population adolescent and young adult twin sample (n = 704), the association between white noise speech illusion and subclinical psychotic experiences, using the Structured Interview for Schizotypy-Revised (SIS-R) and the Community Assessment of Psychic Experiences (CAPE), was analyzed using multilevel logistic regression analyses.

RESULTS: Perception of any white noise speech illusion was not associated with either positive or negative schizotypy in the general population twin sample, using the method by Galdos et al. (2011) (positive: ORadjusted: 0.82, 95% CI: 0.6-1.12, p = 0.217; negative: ORadjusted: 0.75, 95% CI: 0.56-1.02, p = 0.065) and the method by Catalan et al. (2014) (positive: ORadjusted: 1.11, 95% CI: 0.79-1.57, p = 0.557). No association was found between CAPE scores and speech illusion (ORadjusted: 1.25, 95% CI: 0.88-1.79, p = 0.220). For the Catalan et al. (2014) but not the Galdos et al. (2011) method, a negative association was apparent between positive schizotypy and speech illusion with positive or negative affective valence (ORadjusted: 0.44, 95% CI: 0.24-0.81, p = 0.008).

CONCLUSION: Contrary to findings in clinical populations, white noise speech illusion may not be associated with psychosis proneness in nonclinical populations.

Original languageEnglish
Article numbere0183695
JournalPLOS ONE
Volume12
Issue number8
DOIs
Publication statusPublished - 2017

Fingerprint

Psychotic Disorders
Population
signs and symptoms (animals and humans)
methodology
young adults
sampling
Logistics
Young Adult
interviews
Logistic Models
Regression Analysis
Interviews

Keywords

  • Adolescent
  • Adult
  • Female
  • Humans
  • Male
  • Noise
  • Schizotypal Personality Disorder/physiopathology
  • Speech
  • Young Adult

Cite this

Pries, L-K., Guloksuz, S., Menne-Lothmann, C., Decoster, J., van Winkel, R., Collip, D., ... van Os, J. (2017). White noise speech illusion and psychosis expression: An experimental investigation of psychosis liability. PLOS ONE, 12(8), [e0183695]. https://doi.org/10.1371/journal.pone.0183695
Pries, Lotta-Katrin ; Guloksuz, Sinan ; Menne-Lothmann, Claudia ; Decoster, Jeroen ; van Winkel, Ruud ; Collip, Dina ; Delespaul, Philippe ; De Hert, Marc ; Derom, Catherine ; Thiery, Evert ; Jacobs, Nele ; Wichers, Marieke ; Simons, Claudia J P ; Rutten, Bart P F ; van Os, Jim. / White noise speech illusion and psychosis expression : An experimental investigation of psychosis liability. In: PLOS ONE. 2017 ; Vol. 12, No. 8.
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abstract = "BACKGROUND: An association between white noise speech illusion and psychotic symptoms has been reported in patients and their relatives. This supports the theory that bottom-up and top-down perceptual processes are involved in the mechanisms underlying perceptual abnormalities. However, findings in nonclinical populations have been conflicting.OBJECTIVES: The aim of this study was to examine the association between white noise speech illusion and subclinical expression of psychotic symptoms in a nonclinical sample. Findings were compared to previous results to investigate potential methodology dependent differences.METHODS: In a general population adolescent and young adult twin sample (n = 704), the association between white noise speech illusion and subclinical psychotic experiences, using the Structured Interview for Schizotypy-Revised (SIS-R) and the Community Assessment of Psychic Experiences (CAPE), was analyzed using multilevel logistic regression analyses.RESULTS: Perception of any white noise speech illusion was not associated with either positive or negative schizotypy in the general population twin sample, using the method by Galdos et al. (2011) (positive: ORadjusted: 0.82, 95{\%} CI: 0.6-1.12, p = 0.217; negative: ORadjusted: 0.75, 95{\%} CI: 0.56-1.02, p = 0.065) and the method by Catalan et al. (2014) (positive: ORadjusted: 1.11, 95{\%} CI: 0.79-1.57, p = 0.557). No association was found between CAPE scores and speech illusion (ORadjusted: 1.25, 95{\%} CI: 0.88-1.79, p = 0.220). For the Catalan et al. (2014) but not the Galdos et al. (2011) method, a negative association was apparent between positive schizotypy and speech illusion with positive or negative affective valence (ORadjusted: 0.44, 95{\%} CI: 0.24-0.81, p = 0.008).CONCLUSION: Contrary to findings in clinical populations, white noise speech illusion may not be associated with psychosis proneness in nonclinical populations.",
keywords = "Adolescent, Adult, Female, Humans, Male, Noise, Schizotypal Personality Disorder/physiopathology, Speech, Young Adult",
author = "Lotta-Katrin Pries and Sinan Guloksuz and Claudia Menne-Lothmann and Jeroen Decoster and {van Winkel}, Ruud and Dina Collip and Philippe Delespaul and {De Hert}, Marc and Catherine Derom and Evert Thiery and Nele Jacobs and Marieke Wichers and Simons, {Claudia J P} and Rutten, {Bart P F} and {van Os}, Jim",
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Pries, L-K, Guloksuz, S, Menne-Lothmann, C, Decoster, J, van Winkel, R, Collip, D, Delespaul, P, De Hert, M, Derom, C, Thiery, E, Jacobs, N, Wichers, M, Simons, CJP, Rutten, BPF & van Os, J 2017, 'White noise speech illusion and psychosis expression: An experimental investigation of psychosis liability', PLOS ONE, vol. 12, no. 8, e0183695. https://doi.org/10.1371/journal.pone.0183695

White noise speech illusion and psychosis expression : An experimental investigation of psychosis liability. / Pries, Lotta-Katrin; Guloksuz, Sinan; Menne-Lothmann, Claudia; Decoster, Jeroen; van Winkel, Ruud; Collip, Dina; Delespaul, Philippe; De Hert, Marc; Derom, Catherine; Thiery, Evert; Jacobs, Nele; Wichers, Marieke; Simons, Claudia J P; Rutten, Bart P F; van Os, Jim.

In: PLOS ONE, Vol. 12, No. 8, e0183695, 2017.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - White noise speech illusion and psychosis expression

T2 - An experimental investigation of psychosis liability

AU - Pries, Lotta-Katrin

AU - Guloksuz, Sinan

AU - Menne-Lothmann, Claudia

AU - Decoster, Jeroen

AU - van Winkel, Ruud

AU - Collip, Dina

AU - Delespaul, Philippe

AU - De Hert, Marc

AU - Derom, Catherine

AU - Thiery, Evert

AU - Jacobs, Nele

AU - Wichers, Marieke

AU - Simons, Claudia J P

AU - Rutten, Bart P F

AU - van Os, Jim

PY - 2017

Y1 - 2017

N2 - BACKGROUND: An association between white noise speech illusion and psychotic symptoms has been reported in patients and their relatives. This supports the theory that bottom-up and top-down perceptual processes are involved in the mechanisms underlying perceptual abnormalities. However, findings in nonclinical populations have been conflicting.OBJECTIVES: The aim of this study was to examine the association between white noise speech illusion and subclinical expression of psychotic symptoms in a nonclinical sample. Findings were compared to previous results to investigate potential methodology dependent differences.METHODS: In a general population adolescent and young adult twin sample (n = 704), the association between white noise speech illusion and subclinical psychotic experiences, using the Structured Interview for Schizotypy-Revised (SIS-R) and the Community Assessment of Psychic Experiences (CAPE), was analyzed using multilevel logistic regression analyses.RESULTS: Perception of any white noise speech illusion was not associated with either positive or negative schizotypy in the general population twin sample, using the method by Galdos et al. (2011) (positive: ORadjusted: 0.82, 95% CI: 0.6-1.12, p = 0.217; negative: ORadjusted: 0.75, 95% CI: 0.56-1.02, p = 0.065) and the method by Catalan et al. (2014) (positive: ORadjusted: 1.11, 95% CI: 0.79-1.57, p = 0.557). No association was found between CAPE scores and speech illusion (ORadjusted: 1.25, 95% CI: 0.88-1.79, p = 0.220). For the Catalan et al. (2014) but not the Galdos et al. (2011) method, a negative association was apparent between positive schizotypy and speech illusion with positive or negative affective valence (ORadjusted: 0.44, 95% CI: 0.24-0.81, p = 0.008).CONCLUSION: Contrary to findings in clinical populations, white noise speech illusion may not be associated with psychosis proneness in nonclinical populations.

AB - BACKGROUND: An association between white noise speech illusion and psychotic symptoms has been reported in patients and their relatives. This supports the theory that bottom-up and top-down perceptual processes are involved in the mechanisms underlying perceptual abnormalities. However, findings in nonclinical populations have been conflicting.OBJECTIVES: The aim of this study was to examine the association between white noise speech illusion and subclinical expression of psychotic symptoms in a nonclinical sample. Findings were compared to previous results to investigate potential methodology dependent differences.METHODS: In a general population adolescent and young adult twin sample (n = 704), the association between white noise speech illusion and subclinical psychotic experiences, using the Structured Interview for Schizotypy-Revised (SIS-R) and the Community Assessment of Psychic Experiences (CAPE), was analyzed using multilevel logistic regression analyses.RESULTS: Perception of any white noise speech illusion was not associated with either positive or negative schizotypy in the general population twin sample, using the method by Galdos et al. (2011) (positive: ORadjusted: 0.82, 95% CI: 0.6-1.12, p = 0.217; negative: ORadjusted: 0.75, 95% CI: 0.56-1.02, p = 0.065) and the method by Catalan et al. (2014) (positive: ORadjusted: 1.11, 95% CI: 0.79-1.57, p = 0.557). No association was found between CAPE scores and speech illusion (ORadjusted: 1.25, 95% CI: 0.88-1.79, p = 0.220). For the Catalan et al. (2014) but not the Galdos et al. (2011) method, a negative association was apparent between positive schizotypy and speech illusion with positive or negative affective valence (ORadjusted: 0.44, 95% CI: 0.24-0.81, p = 0.008).CONCLUSION: Contrary to findings in clinical populations, white noise speech illusion may not be associated with psychosis proneness in nonclinical populations.

KW - Adolescent

KW - Adult

KW - Female

KW - Humans

KW - Male

KW - Noise

KW - Schizotypal Personality Disorder/physiopathology

KW - Speech

KW - Young Adult

U2 - 10.1371/journal.pone.0183695

DO - 10.1371/journal.pone.0183695

M3 - Article

C2 - 28832672

VL - 12

JO - PLOS ONE

JF - PLOS ONE

SN - 1932-6203

IS - 8

M1 - e0183695

ER -

Pries L-K, Guloksuz S, Menne-Lothmann C, Decoster J, van Winkel R, Collip D et al. White noise speech illusion and psychosis expression: An experimental investigation of psychosis liability. PLOS ONE. 2017;12(8). e0183695. https://doi.org/10.1371/journal.pone.0183695